This tool helps researchers and veterinarians to calculate doses of analgesic, anesthetic and streptosotozin. Labinsane calculates intraperitoneal dose of streptozotocin for induction of diabetes in mice with a single dose (1). In addition, a formula is added to calculate the dose for anesthesia induction in C57 and Swiss micen (2), in order to reduce the risk of applying a higher or lower dose of these medicines and thus save time, animals and limited resources.
1= Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Global J Pharmacol. 2009;3(2):81-4.
2= Jaber SM, Hankenson FC, Heng K, McKinstry-Wu A, Kelz MB, Marx JO. Dose Regimens, Variability, and Complications Associated with Using Repeat-Bolus Dosing to Extend a Surgical Plane of Anesthesia in Laboratory Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(6):684-91
1= Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Global J Pharmacol. 2009;3(2):81-4.
2= Jaber SM, Hankenson FC, Heng K, McKinstry-Wu A, Kelz MB, Marx JO. Dose Regimens, Variability, and Complications Associated with Using Repeat-Bolus Dosing to Extend a Surgical Plane of Anesthesia in Laboratory Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(6):684-91
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